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Hypoxic tumor environments exhibit disrupted collagen I fibers and low macromolecular transport.

Hypoxic tumor microenvironments result in an aggressive phenotype and resistance to therapy that lead to tumor progression, recurrence, and metastasis. While poor vascularization and the resultant inadequate drug delivery are known to contribute to drug resistance, the effect of hypoxia on molecular...

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Gorde:
Egile Nagusiak: Samata M Kakkad, Marie-France Penet, Alireza Akhbardeh, Arvind P Pathak, Meiyappan Solaiyappan, Venu Raman, Dieter Leibfritz, Kristine Glunde, Zaver M Bhujwalla
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2013-01-01
Saila:PLoS ONE
Sarrera elektronikoa:https://doi.org/10.1371/journal.pone.0081869
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