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HDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophy.

Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington's disease (HD). While HD has been described primarily as a...

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Detaylı Bibliyografya
Asıl Yazarlar: Michal Mielcarek, Marta Toczek, Cleo J L M Smeets, Sophie A Franklin, Marie K Bondulich, Nelly Jolinon, Thomas Muller, Mhoriam Ahmed, James R T Dick, Izabela Piotrowska, Linda Greensmith, Ryszard T Smolenski, Gillian P Bates
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2015-03-01
Seri Bilgileri:PLoS Genetics
Online Erişim:http://europepmc.org/articles/PMC4352047?pdf=render
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