Dystrophin Is Required for the Proper Timing in Retinal Histogenesis: A Thorough Investigation on the mdx Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a lethal X-linked muscular disease caused by defective expression of the cytoskeletal protein dystrophin (Dp427). Selected autonomic and central neurons, including retinal neurons, express Dp427 and/or dystrophin shorter isoforms. Because of this, DMD patients ma...

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Hauptverfasser:	Irene Persiconi, Francesca Cosmi, Noemi Antonella Guadagno, Giuseppe Lupo, Maria Egle De Stefano
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2020-08-01
Schriftenreihe:	Frontiers in Neuroscience
Schlagworte:	Duchenne muscular dystrophy mdx mice dystrophin retinogenesis retinal ganglion cells GABA
Online-Zugang:	https://www.frontiersin.org/article/10.3389/fnins.2020.00760/full
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