Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease

The DNA damage response (DDR) pathway is upregulated in autosomal dominant polycystic kidney disease (ADPKD) but its functional role is not known. The ataxia-telangiectasia mutated (ATM) and AT and Rad3-related (ATR) protein kinases are key proximal transducers of the DDR. This study hypothesized th...

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Hlavní autoři:	Jennifer Q. J. Zhang, Sayanthooran Saravanabavan, Gopala K. Rangan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-03-01
Edice:	Cells
Témata:	autosomal dominant polycystic kidney disease DNA damage response ATM ATR
On-line přístup:	https://www.mdpi.com/2073-4409/10/3/532
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