Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa

Abstract Background Parasite genetic diversity and multiplicity of infection (MOI) affect clinical outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity. Traditional methods often underestimate the frequency and diversity of multiclonal infections due to technical s...

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Detalhes bibliográficos

Principais autores:	Daibin Zhong, Eugenia Lo, Xiaoming Wang, Delenasaw Yewhalaw, Guofa Zhou, Harrysone E. Atieli, Andrew Githeko, Elizabeth Hemming-Schroeder, Ming-Chieh Lee, Yaw Afrane, Guiyun Yan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-05-01
coleção:	Malaria Journal
Assuntos:	Multiplicity of infection Merozoite surface protein 1 Amplicon deep sequencing Molecular epidemiology Plasmodium Within-host diversity
Acesso em linha:	http://link.springer.com/article/10.1186/s12936-018-2337-y
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