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Zolbetuximab: A Narrative Drug Review

Claudin-18.2 (CLDN18.2) is a tight junction protein selectively expressed in a subset of gastric and gastroesophageal junction (GEJ) adenocarcinomas, making it a promising therapeutic target. Zolbetuximab is a first-in-class chimeric IgG1 monoclonal antibody that binds to CLDN18.2-positive tumor cel...

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Bibliografiske detaljer
Principais autores: Alma Rose Devasia, Keechilat Pavithran
Format: Artigo
Sprog:Inglês
Udgivet: Thieme Medical and Scientific Publishers Pvt. Ltd.
Serier:Indian Journal of Medical and Paediatric Oncology
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Online adgang:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0046-1816546
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