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A comparison of basal and activity-dependent exon splicing in cortical-patterned neurons of human and mouse origin

Rodent studies have shown that alternative splicing in neurons plays important roles in development and maturity, and is regulatable by signals such as electrical activity. However, rodent-human similarities are less well explored. We compared basal and activity-dependent exon splicing in cortical-p...

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Wedi'i Gadw mewn:
Prif Awduron: Owen Dando, Jamie McQueen, Karen Burr, Peter C. Kind, Siddharthan Chandran, Giles E. Hardingham, Jing Qiu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2024-08-01
Cyfres:Frontiers in Molecular Neuroscience
Pynciau:
RNA-seq-RNA sequencing
gene expression
neuronal activity
calcium signaling
evolutionary conservation and divergence
alternative splicing
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1392408/full
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