In vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the Amazonian plant Tachia grandiflora (Gentianaceae)

Tachia sp. are used as antimalarials in the Amazon Region and in vivo antimalarial activity of a Tachia sp. has been previously reported. Tachia grandiflora Maguire and Weaver is an Amazonian antimalarial plant and herein its cytotoxicity and antimalarial activity were investigated. Spectral analysi...

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Detalhes bibliográficos

Principais autores:	Luiz Francisco Rocha e Silva, Emerson Silva Lima, Marne Carvalho de Vasconcellos, Ellen Suzany Pereira Aranha, David Siqueira Costa, Elba Vieira Mustafa, Sabrina Kelly Reis de Morais, Maria das Gracas Costa Alecrim, Sergio Massayoshi Nunomura, Lena Struwe, Valter Ferreira de Andrade-Neto, Adrian Martin Pohlit
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Fundação Oswaldo Cruz (FIOCRUZ) 2013-06-01
coleção:	Memorias do Instituto Oswaldo Cruz
Assuntos:	amplexine (djalonenol) decussatin Plasmodium falciparum Plasmodium berghei human fibroblasts
Acesso em linha:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000400501&lng=en&tlng=en
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