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Evaluation of the Combined Effect of 2ME2 and Co on the Inducement of DNA Damage by IUdR in a Spheroid Model of the U87MG Glioblastoma Cancer Cell Line Using Alkaline Comet Assay

Objective: In this study, we investigated the combined effect of 2-Methoxyestradiol (2ME2)and 60Co on the cytogenetic damage of iododeoxyuridine (IUdR) in the spheroid model ofU87MG glioblastoma cancer cell lines by alkaline comet assay.Materials and Methods: U87MG cells were cultured as spheroids w...

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Principais autores: Ali Neshasteh-Riz, Seyed Rabi Mahdavi, Samideh Khoei, Sara Delfan
Format: Artigo
Sprog:Inglês
Udgivet: Royan Institute (ACECR), Tehran 2011-01-01
Serier:Cell Journal
Fag:
Iododeoxyuridinre
DNA Damage
HIF-1Alpha
2-Methoxyestradiol
Comet
Online adgang:http://www.celljournal.org/library/upload/article/af_2285444223845624662322274543555736324432Khoei.pdf
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