Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/reperfusion injury in mice

Following myocardial infarction (MI), elderly patients have a poorer prognosis than younger patients, which may be linked to increased coronary microvessel susceptibility to injury. Interleukin-36 (IL-36), a newly discovered proinflammatory member of the IL-1 superfamily, may mediate this injury, bu...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Juma El-Awaisi, Dean P.J. Kavanagh, Marco R. Rink, Chris J. Weston, Nigel E. Drury, Neena Kalia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical investigation 2022-03-01
Colecção:	JCI Insight
Assuntos:	Aging Inflammation
Acesso em linha:	https://doi.org/10.1172/jci.insight.155236
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!