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In Vivo Predictive Dissolution (IPD) for Carbamazepine Formulations: Additional Evidence Regarding a Biopredictive Dissolution Medium

The aim of the present study was to bring additional evidence regarding a biopredictive dissolution medium containing 1% sodium lauryl sulphate (SLS) to predict the in vivo behavior of carbamazepine (CBZ) products. Twelve healthy volunteers took one immediate release (IR) dose of either test and ref...

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Principais autores: Marival Bermejo, Jessica Meulman, Marcelo Gomes Davanço, Patricia de Oliveira Carvalho, Isabel Gonzalez-Alvarez, Daniel Rossi Campos
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-06-01
Serier:Pharmaceutics
Fag:
carbamazepine
in vitro in vivo correlation
dissolution
biopredictive
bioequivalence
biowaiver
Online adgang:https://www.mdpi.com/1999-4923/12/6/558
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