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Accelerated brain atrophy in sickle cell anemia despite chronic exchange transfusion therapy—A case report

Neurovascular complications are a common and major cause of morbidity and mortality in patients with sickle cell anemia (SCA). Prior studies have demonstrated cortical thinning as well as reduced cerebral volume in children with SCA when compared to age-matched controls, but data in adults are scarc...

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Principais autores: Tales Santini, PhD, Jinghang Li, Jr-Jiun Liou, PhD, Sossena Wood, PhD, Howard J. Aizenstein, MD, PhD, Joseph Mettenburg, MD, PhD, Enrico M. Novelli, MD, MS, Tamer S. Ibrahim, PhD, Olubusola Oluwole, MD, MS
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-04-01
coleção:Radiology Case Reports
Assuntos:
Sickle cell anemia
Cerebral atrophy
Chronic exchange transfusion therapy
7T MRI
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1930043325011471
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