Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer

Abstract Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes are likely to fall within this phenotypi...

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Bibliografiske detaljer

Principais autores:	Sigurdur Trausti Karvelsson, Qiong Wang, Bylgja Hilmarsdottir, Arnar Sigurdsson, Siver Andreas Moestue, Gunhild Mari Mælandsmo, Skarphedinn Halldorsson, Steinn Gudmundsson, Ottar Rolfsson
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2021-09-01
Serier:	npj Systems Biology and Applications
Online adgang:	https://doi.org/10.1038/s41540-021-00195-5
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