Extracellular vesicles from cancer cell lines of different origins drive the phenotype of normal oral fibroblasts in a CAF-like direction

IntroductionNormal oral fibroblasts (NOFs) are located in the connective tissue of the oral mucosa. The NOFs play an important role in wound healing, tumor progression, and metastasis. They are subjected to influence by external and internal stimuli, among them extracellular vesicles (EVs), that are...

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Principais autores:	Tine M. Søland, Aleksandra Lipka, Ann-Kristin Ruus, Ann-Kristin Molværsmyr, Hilde K. Galtung, Trude M. Haug
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-09-01
coleção:	Frontiers in Oncology
Assuntos:	oral cancer oral squamous cell carcinoma cancer-associated fibroblasts phenotype proliferation migration
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1456346/full
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