The ketogenic diet increases Neuregulin 1 expression via elevating histone acetylation and its anti-seizure effect requires ErbB4 kinase activity

Abstract Background The ketogenic diet (KD)has been considered an effective treatment for epilepsy, whereas its underlying mechanisms remain obscure. We have previously reported that the KD feeding increased Neuregulin 1 (NRG1) expression in the hippocampus; disruption of NRG1 signaling by genetical...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Jin Wang, Jie Huang, Shan Yao, Jia-Hui Wu, Hui-Bin Li, Feng Gao, Ying Wang, Guo-Bin Huang, Qiang-Long You, Jianhua Li, Xiaohui Chen, Xiang-Dong Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-05-01
coleção:	Cell & Bioscience
Assuntos:	Neuregulin 1 Ketogenic diet Acetylation ErbB4 kinase activity Epilepsy
Acesso em linha:	https://doi.org/10.1186/s13578-021-00611-7
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!