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Exaggerated postnatal surge of orexin neurons and the effects of elimination of excess orexin on blood pressure and exaggerated chemoreflex in spontaneously hypertensive rats

An overactive orexin (OX) system is associated with neurogenic hypertension and an exaggerated chemoreflex in spontaneously hypertensive rats (SHRs). However, the chronology and mechanism of this association is unclear. We hypothesized that increased postnatal neurogenesis of OX neurons in SHRs prec...

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Detalhes bibliográficos
Principais autores: Savannah Lusk, Alexander M. Moushey, Nicholas Iwakoshi, Christopher G. Wilson, Aihua Li, Russell Ray
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-10-01
coleção:Frontiers in Physiology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphys.2024.1341649/full
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