Thymic Atrophy and Apoptosis of CD4+CD8+ Thymocytes in the Cuprizone Model of Multiple Sclerosis.

Previous studies on the degenerative animal model of multiple sclerosis suggested that the copper-chelator cuprizone might directly suppress T-cell functions. Peripheral T-cell function in the cuprizone model has already been explored; therefore, in the present study, we investigated, for the first...

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Auteurs principaux:	Izabella Solti, Krisztian Kvell, Gergely Talaber, Sara Veto, Peter Acs, Ferenc Gallyas, Zsolt Illes, Katalin Fekete, Petra Zalan, Arpad Szanto, Zita Bognar
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2015-01-01
Collection:	PLoS ONE
Accès en ligne:	http://europepmc.org/articles/PMC4460035?pdf=render
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