Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights

Down Syndrome (DS) is the most common genetic cause of intellectual disability, in which an extra copy of human chromosome 21 (HSA21) affects regional DNA methylation profiles across the genome. Although DNA methylation has been previously examined at select regulatory regions across the genome in a...

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Egile Nagusiak:	Benjamin I. Laufer, Hyeyeon Hwang, Annie Vogel Ciernia, Charles E. Mordaunt, Janine M. LaSalle
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis Group 2019-07-01
Saila:	Epigenetics
Gaiak:	epigenomics dna methylation whole genome bisulfite sequencing wgbs differentially methylated regions dmrs down syndrome brain
Sarrera elektronikoa:	http://dx.doi.org/10.1080/15592294.2019.1609867
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