Fluid Shear Stress-Induced Exosomes from Liver Cancer Cells Promote Activation of Cancer-Associated Fibroblasts via IGF2-PI3K Axis

Background: Cancer-associated fibroblasts (CAFs) are of considerable importance in tumor progression by interacting with the tumor microenvironment. However, the hidden mechanism explaining how tumor cells interact with CAFs in the tumor mechanical microenvironment remains largely unknown. Methods:...

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Detalhes bibliográficos

Principais autores:	Tang Feng, Fei Fang, Chunhe Zhang, Tiantian Li, Jia He, Yang Shen, Hongchi Yu, Xiaoheng Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	IMR Press 2022-03-01
coleção:	Frontiers in Bioscience-Landmark
Assuntos:	fluid shear stress cancer-associated fibroblasts exosome igf2 cell-cell communication
Acesso em linha:	https://www.imrpress.com/journal/FBL/27/3/10.31083/j.fbl2703104
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