A vitamin E long-chain metabolite and the inspired drug candidate α-amplexichromanol relieve asthma features in an experimental model of allergen sensitization

Benefits for vitamin E intake in diseases with inflammatory components have been described and related in part, to endogenously formed metabolites (long-chain metabolites, LCM). Here, we have evaluated the role of LCM in relieving asthma features. To this aim, the endogenous vitamin E metabolite α-1...

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Үндсэн зохиолчид:	Ida Cerqua, Konstantin Neukirch, Michela Terlizzi, Elisabetta Granato, Elisabetta Caiazzo, Carla Cicala, Armando Ialenti, Raffaele Capasso, Oliver Werz, Rosalinda Sorrentino, Denis Seraphin, Jean-Jacques Helesbeux, Giuseppe Cirino, Andreas Koeberle, Fiorentina Roviezzo, Antonietta Rossi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2022-07-01
Цуврал:	Pharmacological Research
Нөхцлүүд:	α-13′-carboxychromanol α-amplexichromanol Vitamin E Bronchial hyperreactivity Cyclooxygenase Lipoxygenase
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1043661822001955
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!