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Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function

The miR-1/133/206 gene family codes for the most abundant microRNAs in striated muscles. Here, Klockner et al show that inactivation of all family members in skeletal muscle prevents formation of normal neuromuscular junctions due to increased expression of the adaptor protein CRK.

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書誌詳細
主要な著者: Ina Klockner, Christian Schutt, Theresa Gerhardt, Thomas Boettger, Thomas Braun
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2022-06-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-022-30778-7
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