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Tau condensation on DNA mediates microtubule attachment suggesting a mitotic role for centromere-localized tau

Abstract Tau protein, traditionally recognized for stabilizing microtubules and forming pathological aggregates, has recently been observed to form condensates in various contexts. While its condensation with RNA has been well studied, the interaction between tau and DNA, along with its biological s...

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Detalhes bibliográficos
Principais autores: Celine Park, Jaehun Jung, Yuri Hong, Haeun Yoo, Keunsang Yang, Jaehyeon Shin, Minsik Kim, Chan Lim, Ayoung Jeong, Seokyun Hong, Jun Young Baek, Sang-Hyun Rah, Chaelin Lee-Eom, Minseok Seo, Yoori Kim, Jae-Hyung Jeon, Jong-Bong Lee, Dong Soo Hwang, Min Ju Shon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2026-01-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-025-67888-x
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