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Application-Oriented Bulk Cryopreservation of Human iPSCs in Cryo Bags Followed by Direct Inoculation in Scalable Suspension Bioreactors for Expansion and Neural Differentiation

Stem cell-based therapies are promising tools for regenerative medicine and require bulk numbers of high-quality cells. Currently, cells are produced on demand and have a limited shelf-life as conventional cryopreservation is primarily designed for stock keeping. We present a study on bulk cryoprese...

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Principais autores: Ina Meiser, Monica Alstrup, Elham Khalesi, Bianca Stephan, Anna M. Speicher, Julia Majer, Chee Keong Kwok, Julia C. Neubauer, Mattias Hansson, Heiko Zimmermann
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-07-01
coleção:Cells
Assuntos:
hiPSC
cryopreservation
suspension bioreactors
cell therapy
bulk
expansion
Acesso em linha:https://www.mdpi.com/2073-4409/12/14/1914
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