On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular Cancer
Human primordial germ cells (PGCs) have been described in the yolk sac wall around the beginning of the third week. From week 4 to 5, they migrate under control of SCF/c-KIT signaling pathway to the genital ridge, where they become gonocytes. PGCs and gonocytes express classic pluripotency markers,...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2019-06-01
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| Schriftenreihe: | Frontiers in Endocrinology |
| Schlagworte: | |
| Online-Zugang: | https://www.frontiersin.org/article/10.3389/fendo.2019.00343/full |
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