Development and Formulation of Nanofiber-Based Ophthalmic Inserts for the Treatment of Fungal Keratitis

<b>Background/Objectives</b>: Fungal keratitis remains a vision-threatening infection, and current amphotericin B (AmphB) eye drops suffer from low corneal residence time, poor aqueous solubility, and the need for frequent dosing. This study develops electrospun nanofiber-based ophthalmic inserts co...

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Bibliografische Detailangaben

Hauptverfasser:	Safaa Omer, Nándor Nagy, Júlia Pongrácz, Bence Dávid Tóth, Balázs Pinke, László Mészáros, Katalin Kristóf, Adrienn Kazsoki, Romána Zelkó
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-04-01
Schriftenreihe:	Pharmaceutics
Schlagworte:	accelerated stability test amphotericin B-loaded nanofibers cytocompatibility study fungal keratitis in vitro antifungal efficacy in vitro drug release study
Online-Zugang:	https://www.mdpi.com/1999-4923/18/4/464
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