Protein trans-splicing: optimization of intein-mediated GFP assembly as a model for the development of gene therapy
Adeno-associated virus (AAV)-based gene therapy has become one of the key directions of modern translational medicine geared towards treatment of hereditary disorders by means of gene replacement. At the moment, about 5,000 different syndromes are associated with mutations in large genes, which pres...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2024-11-01
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| Col·lecció: | Frontiers in Bioengineering and Biotechnology |
| Matèries: | |
| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1488912/full |
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