The Symmetrical Wave Pattern of Base-Pair Substitution Rates across the <named-content content-type="genus-species">Escherichia coli</named-content> Chromosome Has Multiple Causes

ABSTRACT Mutation accumulation experiments followed by whole-genome sequencing have revealed that, for several bacterial species, the rate of base-pair substitutions (BPSs) is not constant across the chromosome but varies in a wave-like pattern that is symmetrical about the origin of replication. Th...

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Autors principals:	Brittany A. Niccum, Heewook Lee, Wazim MohammedIsmail, Haixu Tang, Patricia L. Foster
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2019-08-01
Col·lecció:	mBio
Matèries:	Escherichia coli mismatch repair mutation accumulation mutation rate nucleoid-associated proteins nucleoside triphosphate pools
Accés en línia:	https://journals.asm.org/doi/10.1128/mBio.01226-19
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