Roles of Post-translational Modifications in Spinocerebellar Ataxias

Post-translational modifications (PTMs), including phosphorylation, acetylation, ubiquitination, SUMOylation, etc., of proteins can modulate protein properties such as intracellular distribution, activity, stability, aggregation, and interactions. Therefore, PTMs are vital regulatory mechanisms for...

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Auteurs principaux:	Linlin Wan, Keqin Xu, Zhao Chen, Beisha Tang, Hong Jiang
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2018-09-01
Collection:	Frontiers in Cellular Neuroscience
Sujets:	post-translational modification spinocerebellar ataxias protein pathogenesis therapy
Accès en ligne:	https://www.frontiersin.org/article/10.3389/fncel.2018.00290/full
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