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PACAP and Maxadilan (PAC1 Agonist) Influence Plaque Progression, Migratory Ability, and Mitochondrial Morphology and Dynamics in Vascular Smooth Muscle Cells

Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) functions as an anti-atherogenic neuropeptide. Maxadilan, a PAC1 receptor agonist, offers atheroprotection by acting downstream of vascular inflammation caused by hypercholesterolemia. This study aims to explore how PACAP and Max...

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Hauptverfasser: Julia Brauschke, Lisa-Marie Schütz, Gabriel A. Bonaterra, Ralf Kinscherf, Anja Schwarz
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2026-06-01
Schriftenreihe:Cells
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Online-Zugang:https://www.mdpi.com/2073-4409/15/12/1127
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