Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats

Our current research aims to examine whether protocatechuic acid (PCA) can be used as a therapeutic agent for the development of cerebral aneurysm (CA) and to elucidate the mechanisms behind this. We assessed the effects of PCA at 50 and 100 mg/kg on the activation of signaling pathways for tissue n...

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Váldodahkkit:	Xiao Gang, Zhang Mei, Peng Xing, Jiang Guangyuan
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	De Gruyter 2021-02-01
Ráidu:	Open Life Sciences
Fáttát:	cerebral aneurysm protocatechuic acid macrophages inflammatory response mechanisms chemokines tnf-α signaling, nrf-2
Liŋkkat:	https://doi.org/10.1515/biol-2021-0012
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