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Identification of a tumor-specific allo-HLA–restricted γδTCR

Abstract: γδT cells are key players in cancer immune surveillance because of their ability to recognize malignant transformed cells, which makes them promising therapeutic tools in the treatment of cancer. However, the biological mechanisms of how γδT-cell receptors (TCRs) interact with their ligand...

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Hauptverfasser: G.J.J. Kierkels, W. Scheper, A.D. Meringa, I. Johanna, D.X. Beringer, A. Janssen, M. Schiffler, T. Aarts-Riemens, L. Kramer, T. Straetemans, S. Heijhuurs, J.H.W. Leusen, E. San José, K. Fuchs, M. Griffioen, J.H. Falkenburg, L. Bongiovanni, A. de Bruin, D. Vargas-Diaz, M. Altelaar, A.J.R. Heck, L.D. Shultz, F. Ishikawa, M.I. Nishimura, Z. Sebestyén, J. Kuball
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019-10-01
Schriftenreihe:Blood Advances
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2473952920318504
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