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Cytokine imbalance and HBV-specific T-cell exhaustion predict disease progression in HIV-HBV coinfection

BackgroundHIV-HBV coinfection accelerates liver disease, yet the immunological mechanisms underlying adverse outcomes remain incompletely characterized in African populations. We investigated relationships between HBV reactivation, cytokine dysregulation, T-cell dysfunction, and disease progression...

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Hauptverfasser: Peter Asaga Mac, Dave C. Ibeh, Mansur Aliyu Ramalan, Bako A. Ishaku
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-03-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1789692/full
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