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Activation of TP53 target genes in the primary response of triple-negative breast cancer cells to doxorubicin treatment

Abstract Among the DNA-damaging agents commonly used in clinical settings doxorubicin has emerged as one of the most effective treatments for Triple-negative breast cancer (TNBC). Our limited understanding about the molecular mechanisms underlying the short- and long-term responses of TNBC cells to...

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Autori principali: Aysan Shekari, Yaghub Pazhang, Hamid Maadi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-12-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-31087-x
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