TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

Abstract Background Proliferative vitreoretinopathy (PVR) is a blind-causing disease initiated by the activation of retinal pigmented epithelium (RPE) primarily induced by TGF-β families. Migrasome is a recently discovered type of extracellular vesicle related to cell migration. Results Here, we use...

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Detalhes bibliográficos

Principais autores:	Liangjing Wu, Shuai Yang, Hui Li, Yao Zhang, Le Feng, Conghui Zhang, Jiayi Wei, Xunyi Gu, Guotong Xu, Zhaoyang Wang, Fang Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-12-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Migrasome tetraspanin4 Epithelial–mesenchymal transition Retinal pigmented epithelium Proliferative vitreoretinopathy
Acesso em linha:	https://doi.org/10.1186/s12951-022-01732-y
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