Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases
The design of a constitutively active form of the C-terminal kinase domain of the p90 ribosomal S6 kinase 2 (RSK2) is described, and this is based on a phosphomimetic mutation and a C-terminal truncation, yielding a high kinase activity. The p90 ribosomal S6 kinases (RSKs) contain two distinct catal...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Life Science Alliance LLC
2023-05-01
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| Reeks: | Life Science Alliance |
| Online toegang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202201425 |
| Tags: |
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