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Integration analysis of microRNA and mRNA paired expression profiling identifies deregulated microRNA-transcription factor-gene regulatory networks in ovarian endometriosis

Abstract Background The etiology and pathophysiology of endometriosis remain unclear. Accumulating evidence suggests that aberrant microRNA (miRNA) and transcription factor (TF) expression may be involved in the pathogenesis and development of endometriosis. This study therefore aims to survey the k...

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Main Authors: Luyang Zhao, Chenglei Gu, Mingxia Ye, Zhe Zhang, Li’an Li, Wensheng Fan, Yuanguang Meng
Format: Artigo
Language:Inglês
Published: BMC 2018-01-01
Series:Reproductive Biology and Endocrinology
Subjects:
Endometriosis
Endometrium
MicroRNAs
Transcription factors
Integrative analysis
Online Access:http://link.springer.com/article/10.1186/s12958-017-0319-5
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