Toward the Development of a Live Attenuated Vaccine: Construction and Evaluation of a Salmonella Enteritidis Mutant Strain

This study developed a genetically attenuated Salmonella enteritidis (S. enteritidis) strain, designated as SD01ΔMg (deficient in asd, crp, rfaL, rffG, and rfbB), to enhance vaccine safety while maintaining immunogenicity. The virulence of the mutant strain was evaluated by determining the median le...

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Prif Awduron:	Feng Guan, Yishuo Li, Xiaohan Sun, An Zhang, Hao Gong, Guijuan Hao, Fangkun Wang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2025-12-01
Cyfres:	Veterinary Vaccine
Pynciau:	Salmonella Enteritidis Gene deletion Immune protection Attenuated Salmonella vaccines
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S2772535925000423
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