Predicting host tropism in influenza a viruses: insights from multi-segment nucleotide signatures

Abstract Background Influenza A virus (IAV) poses a significant public health threat due to its cross-species transmission and complex host adaptation mechanisms. This study integrated whole-genome data from avian, human, swine, and bovine IAV strains, using machine learning to predict viral host tr...

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Detalhes bibliográficos

Principais autores:	Weijie Chen, Tingting Pei, Zhan Zhang, Xinyu Liu, Xiaoding He, Jingjing Hu, Shuiping Lu, Qi Chen, Siru Hu, Sijia Zhuang, Jiaxu Chen, Jianlin Zhuang, Chenglong Xiong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Journal of Translational Medicine
Assuntos:	Influenza A viruses Host tropism Predictive modeling Cross-species transmission Nucleotide signature
Acesso em linha:	https://doi.org/10.1186/s12967-025-07569-x
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