Copper and cuproptosis-related genes in hepatocellular carcinoma: therapeutic biomarkers targeting tumor immune microenvironment and immune checkpoints

BackgroundHepatocellular carcinoma (HCC), one of the most common cancers worldwide, exhibits high immune heterogeneity and mortality. Emerging studies suggest that copper (Cu) plays a key role in cell survival. However, the relationship between Cu and tumor development remains unclear.MethodsWe inve...

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Principais autores:	Xiaoqiang Wang, Dongfang Chen, Yumiao Shi, Jiamei Luo, Yiqi Zhang, Xiaohong Yuan, Chaojin Zhang, Huigang Shu, Weifeng Yu, Jie Tian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-04-01
coleção:	Frontiers in Immunology
Assuntos:	copper cuproptosis hepatocellular carcinoma immune checkpoints tumor immune microenvironment
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1123231/full
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