Neutralization of acyl coenzyme A binding protein for the experimental prevention and treatment of hepatocellular carcinoma

Summary: Acyl coenzyme A binding protein (ACBP encoded by diazepam binding inhibitor DBI) is involved in non-malignant liver diseases. Here, we show that DBI mRNA and circulating ACBP/DBI levels are increased in patients with hepatocellular carcinoma (HCC). We investigated its role in hepatocarcinog...

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Principais autores:	Sijing Li, Omar Motiño, Flavia Lambertucci, Jonathan Pol, Hui Chen, Long Pan, Sylvère Durand, Federica Rossin, Claudia Campani, Lucie Poupel, Christophe Klein, Léa Montégut, María Pérez-Lanzón, Gerasimos Anagnostopoulos, Uxia Nogueira-Recalde, Alexandra Cerone, Fanny Aprahamian, Yanbing Dong, Manuela Lizarralde-Guerrero, Enfu Xue, Peng Liu, Liwei Zhao, Hui Pan, Vincent Carbonnier, Sylvie Lachkar, Ester Gloria Saavedra Díaz, Li Sun, Chantal Desdouets, Sabine Colnot, Oliver Kepp, Isabelle Martins, Laurence Zitvogel, Mauro Piacentini, Jean-Charles Nault, Maria Chiara Maiuri, Jessica Zucman-Rossi, Guido Kroemer
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2025-07-01
סדרה:	Cell Reports Medicine
נושאים:	HCC ACBP/DBI inhibition anti-PD-1 proliferation ferroptosis immunotherapy
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2666379125003052
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