The Marine Natural Product Pseudopterosin Blocks Cytokine Release of Triple-Negative Breast Cancer and Monocytic Leukemia Cells by Inhibiting NF-κB Signaling

Pseudopterosins are a group of marine diterpene glycosides which possess an array of biological activities including anti-inflammatory effects. However, despite the striking in vivo anti-inflammatory potential, the underlying in vitro molecular mode of action remains elusive. To date, few studies ha...

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Principais autores:	Julia Sperlich, Russell Kerr, Nicole Teusch
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2017-08-01
coleção:	Marine Drugs
Assuntos:	pseudopterosin NF-κB p65 inflammation tumor microenvironment breast cancer cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor
Acesso em linha:	https://www.mdpi.com/1660-3397/15/9/262
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