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Plasmacytoid dendritic cells in systemic and cutaneous lupus erythematosus: an evolving understanding

Lupus erythematosus is a chronic, heterogenous autoimmune disease driven by a complex interplay of genetic, environmental and hormonal factors, which can manifest as systemic lupus erythematosus (SLE), cutaneous lupus erythematosus (CLE), or both simultaneously. Plasmacytoid dendritic cells (pDCs) a...

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Principais autores: Victoria P. Werth, Lars Rönnblom, Joerg Wenzel, Margaret K. Moseley, Janine Gaiha-Rohrbach, Taylor L. Reynolds, Catherine Barbey, Jane L. Grogan, Marco Colonna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-05-01
coleção:Frontiers in Immunology
Assuntos:
cutaneous lupus erythematosus
plasmacytoid dendritic cells
systemic lupus erythematosus
targeted therapy
type I interferon
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1807771/full
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