The mechanism of ITGB4 in tumor migration and invasion

Integrin β4 (ITGB4) is a transmembrane protein that functions as a mechanosensor, mediating the bidirectional exchange of information between the intracellular and extracellular matrices. ITGB4 plays a critical role in cell adhesion, migration, and signaling. Numerous studies have implicated ITGB4 a...

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Hlavní autoři:	Guichen Huang, Minfeng Zhou, Damin Lu, Jinxiao Li, Qian Tang, Chutong Xiong, Fengxia Liang, Rui Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-08-01
Edice:	Frontiers in Oncology
Témata:	integrin β4 (ITGb4) tumor metastasis cell adhesion epithelialmesenchymal transition (EMT) cancer therapy
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1421902/full
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