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Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects.

A full understanding of gene regulation requires an understanding of the contributions that the various regulatory regions have on gene expression. Although it is well established that sequences downstream of the main promoter can affect expression, our understanding of the scale of this effect and...

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Hlavní autoři: Ophir Shalem, Lucas Carey, Danny Zeevi, Eilon Sharon, Leeat Keren, Adina Weinberger, Orna Dahan, Yitzhak Pilpel, Eran Segal
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS Computational Biology
On-line přístup:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23505350/?tool=EBI
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