Adiponectin Inhibits TNF-α-Activated PAI-1 Expression Via the cAMP-PKA-AMPK-NF-κB Axis in Human Umbilical Vein Endothelial Cells

Background: Tumor necrosis factor (TNF)-α can upregulate the expression of plasminogen activator inhibitor (PAI)-1, an inhibitor of fibrinolysis. Adiponectin (Adp) antagonizes TNF-α by negatively regulating its expression in various tissues. In the present study, the ability of Adp to suppress TNF-α...

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Prif Awduron:	Yijian Chen, Yongliang Zheng, Liping Liu, Chuanming Lin, Changfeng Liao, Liuyan Xin, Sisi Zhong, Qilai Cheng, Liqun Zhang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Cyfres:	Cellular Physiology and Biochemistry
Pynciau:	Antifibrotic effect Binding capability Promoter Plasminogen activator inhibitor Adiponectin
Mynediad Ar-lein:	http://www.karger.com/Article/FullText/480006
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!