Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis

Diabetic cardiomyopathy (DCM) is a serious complication and death cause of diabetes mellitus (DM). Recent cardiology studies suggest that spermidine (SPD) has cardioprotective effects. Here, we verified the hypothesis of SPD’s protective effects on DCM. Therefore, db/db mice and primary neonatal mou...

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Asıl Yazarlar:	Jian Sun, Jiyu Xu, Yong Liu, Yitong Lin, Fengge Wang, Yue Han, Shumin Zhang, Xiaoyan Gao, Changqing Xu, Hui Yuan
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-09-01
Seri Bilgileri:	Biomolecules & Biomedicine
Konular:	Diabetic cardiomyopathy Spermidine ferroptosis Pannexin-1 P2X7
Online Erişim:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/8846
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