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Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.

BACKGROUND:Pneumolysin (PLN) is an intracellular toxin of Streptococcus pneumoniae that has been implicated as a major virulence factor in infections caused by this pathogen. Conserved bacterial motifs are recognized by the immune system by pattern recognition receptors among which the family of Tol...

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Váldodahkkit: Mark C Dessing, Robert A Hirst, Alex F de Vos, Tom van der Poll
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2009-11-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC2776357?pdf=render
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