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Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study

DNA methylation is dynamic, varies throughout the life course, and its levels are influenced by lifestyle and environmental factors, as well as by genetic variation. The leading genetic variants at stroke risk loci identified to date explain roughly 1–2% of stroke heritability. Most of these single...

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Principais autores: Carolina Soriano-Tárraga, Uxue Lazcano, Eva Giralt-Steinhauer, Carla Avellaneda-Gómez, Ángel Ois, Ana Rodríguez-Campello, Elisa Cuadrado-Godia, Alejandra Gómez-González, Alba Fernández-Sanlés, Roberto Elosua, Israel Fernández-Cadenas, Natalia Cullell, Joan Montaner, Sebastian Moran, Manel Esteller, Jordi Jiménez-Conde, Jaume Roquer
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-09-01
coleção:Epigenetics
Assuntos:
ischaemic stroke
dna methylation
ewas
Acesso em linha:http://dx.doi.org/10.1080/15592294.2020.1746507
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