Food phytochemicals, epigallocatechin gallate and myricetin, covalently bind to the active site of the coronavirus main protease in vitro

SARS-CoV-2 main protease is a possible target for protection against viral infection. This study examined the inhibitory effect of food phytochemicals on the main protease of SARS-CoV-2 by determining a cleaved product after chromatographic separation. First, 37 phytochemicals, including glycosides...

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Autors principals:	Yoji Kato, Akari Higashiyama, Emi Takaoka, Miyu Nishikawa, Shinichi Ikushiro
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2021-12-01
Col·lecció:	Advances in Redox Research
Matèries:	Coronavirus main protease Food phytochemical EGCG Myricetin Autoxidation Covalent modification
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2667137921000217
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