Association analysis of polymorphisms rs12997 in ACVR1 and rs1043784 in BMP6 genes involved in bone morphogenic protein signaling pathway in primary angle-closure and pseudoexfoliation glaucoma patients of Saudi origin

Abstract Background Glaucoma is a polygenic neurodegenerative disease and the second most common cause of blindness in Saudi Arabia. To test the hypothesis that genetic variants in the genes involved in the bone morphogenic protein (BMP) signaling pathway may be associated with glaucoma, we investig...

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Principais autores:	Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Essam A. Osman, Faisal A. Almobarak, Saleh A. Al-Obeidan
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2020-07-01
Series:	BMC Medical Genetics
Assuntos:	Activin Transforming growth factor-β Bone morphogenic protein Glaucoma Saudi Arabia Signaling pathway
Acceso en liña:	http://link.springer.com/article/10.1186/s12881-020-01076-0
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